Optimises digestive health: Bifidobacterium longum (ES1) Postbiotic supports gut health and alleviates gastrointestinal symptoms. In a study with diarrhoea-dominant irritable bowel syndrome (IBS) patients, 50 mg[1] of ES1 daily for 12 weeks significantly reduced IBS symptoms, improved stool formation, and enhanced quality of life, with noticeable improvements after 28 days.1  Another trial demonstrated 50 mg of ES1 daily for 8 weeks prevented increases in faecal calprotectin, a marker of gut inflammation. In contrast, the placebo group saw a rise in this inflammatory protein.2 This underscores ES1’s potential in optimising and maintaining digestive health and reducing inflammation in the gut.

Supports a healthy functioning gut by modulating gut motility: Taking BB-12™ at a daily dose of 1 billion CFU significantly increased the frequency of bowel movements in healthy adults with low defecation frequency over 4 weeks, compared to a placebo group. 3

Enhances gut barrier integrity: BB-12™ provides protective effects to the gut by positively influencing the gut microbiome and increasing the synthesis of tight junction proteins, strengthening gut barrier integrity.4,5 In a RCT, BB-12™ at a daily dose of 1 billion CFU demonstrated protective effects on the gut barrier by lowering intestinal permeability in obese adult participants.5 Additionally, ES1 postbiotic reduced gut barrier disruption in an animal study by preserving zonulin levels, a protein that modulates the tight junctions of the gut barrier.6